Bio-remodelling Treatment – “Skin Honey”

Different to a Dermal Filler

And it’s not a Skin Booster

Before Profhilo neck - Bioscor InternationalBefore and after Profhilo neck - Bioscor International
Before Profhilo neck - Bioscor InternationalBefore and after Profhilo neck - Bioscor International
Before Profhilo neck - Bioscor InternationalBefore and after Profhilo neck - Bioscor International

Frequently Asked Questions

The treatment itself is relatively quick and straightforward as only 10 injection points are administered. You will notice the “blobs” for the rest of the day but as “skin honey” has a low viscosity and extreme spreadability, these blobs will soon subside as the product spreads into all areas of the face or neck.

There is minimal downtime with most patients being able to return to work immediately. There will be swelling and pinkness at the injection sites but these will resolve themselves within 48 – 72 hours.

Please note that these “bumps” will be noticeable especially for the first 24 hours but their appearance will improve after a couple days.

It is not recommended that you massage them away in an effort to smooth out the “lumps”. The product protocol is to allow the small mounds of product to slowly and gradually make its way to other areas of the tissue by itself.

Furthermore, by massaging the tissue, you will introduce additional inflammation to the skin which is not ideal in this case.

We highly recommend the following post-care instructions as per the product company’s protocol.

For the first two days (includes the day of treatment), please avoid:

  • Physical strain
  • Sports
  • Any exercise including yoga

For the first two weeks after your treatment, please avoid:

  • Sauna, steam bath, icy temperatures or UV radiation by the sun or solarium (tanning beds)
  • Dental procedures
  • Filler injections in the same are
  • Facial treatments such as microdermabrasion, chemical peels, IPL, skin needling, etc

For 4 weeks after your treatment, please avoid:

  • Fractional resurfacing treatments such as PIXEL, Mosaic, Carbon Dioxide laser resurfacing
  • Any tattoo removals using laser
  • Tattoo treatments/modifications including cosmetic tattoos

It is also highly recommended that you use Profhilo Haenkenium, an anti-oxidant moisturising cream, to help maintain cellular vitality. Created by the same company, its aim is to help reduce amount of hyaluronic acid loss post-treatment. It also works to protect the skin from premature ageing, restores the protective barrier of sensitive and stressed skin as well as improve overall skin quality. Ideally for all skin types, recommended for daily use twice a day for its soothing and moisturising action.

We would recommend two sessions performed 4 weeks apart. Maintenance sessions may be recommended depending on severity of skin laxity.

Yes, it can be dissolved. The enzyme used for traditional dermal fillers (made with hyaluronic acid) will also work for this bio-remodelling injectable as well. However, this product has a high safety profile with no official incidences where dissolving of the product have been required as of September 2022. Note that there has been more than 4.3 million treatments since 2015 and this product is used in more than 80 countries despite it only arriving in Australia in August 2022.


  1. Stellavato A, Corsuto L, D’Agostino A, La Gatta A, Diana P, Bernini P, et al. Hyaluronan Hybrid Cooperative Complexes as a Novel Frontier for Cellular Bioprocesses Re-Activation. PLoS One 2016;11:e0163510.
  2. Hybrid Complexes of High and Low Molecular Weight Hyaluronans Highly Enhance HASCs Differentiation: Implication for Facial Bioremodelling A. Stellavato and M. La Noce et al. Cell Physiol Biochem 2017;44:1078-1092
  3. In vitro analysis of the effects on wound healing of high- and low-molecular weight chains of hyaluronan and their hybrid H-HA/L-HA complexes D’Agostino et al. BMC Cell Biology (2015) 16:19 DOI 10.1186/s12860-015-0064-6