PRF (Platelet-Rich Fibrin) for Hair Loss

Platelet-Rich Fibrin (PRF) is a regenerative, autologous PRF treatment used to support scalp health and the hair follicle environment. It uses a concentrate prepared from your own blood, containing growth factors and cytokines, which is reintroduced into the scalp as part of a broader hair loss management plan.

At Bioscor, PRF for hair loss is offered as a factual, procedure-led option following a health-practitioner consultation. This page explains what PRF is, how it differs from PRP, what the procedure involves, and what to expect from aftercare.

What Is PRF (Platelet-Rich Fibrin)?

PRF is prepared from a small sample of your own blood, spun in a centrifuge to concentrate platelets, growth factors and cytokines within a natural fibrin matrix. Because no anticoagulants or other chemicals are added during preparation, the clotting process is retained, which allows the fibrin scaffold to form.

This fibrin matrix is designed to release growth factors gradually into the scalp tissue, supporting the natural wound-healing response around hair follicles. As an autologous procedure, PRF is often considered by people who prefer a treatment sourced entirely from their own body.

PRF vs PRP: What’s the Difference?

PRP (Platelet-Rich Plasma) was one of the earlier regenerative options used for hair loss, and PRF was developed from it. Both use your own blood, but the preparation differs in a few key ways:

  • Slow, sustained release. PRF’s fibrin matrix supports a gradual release of growth factors over time, rather than a single rapid exposure. PRP preparation uses anticoagulants, which prevents the fibrin matrix from forming.
  • Concentration protocol. PRF is prepared using slower centrifugation speeds over a shorter time, a protocol associated with a higher concentration of growth factors relevant to wound-healing biology.
  • Simpler preparation. PRF doesn’t require anticoagulants or other additives, which may reduce the risk of allergic reaction or sensitivity.

If you’d like more detail on how these two regenerative options compare, our guide to PRP and I-PRF hair regrowth treatments covers the topic further.

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How the PRF Procedure Works

PRF for hair loss follows a structured, in-clinic process. Each step is designed to prepare and deliver your own concentrated growth factors to areas of scalp thinning.

Blood Draw

The process starts with a simple blood draw from your arm, similar to a routine blood test. This is collected using sterile technique and is the only material needed to prepare your PRF solution.

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Horizontal Centrifugation

Your blood sample is then processed in a horizontal centrifuge. Spinning along the horizontal axis, rather than a fixed angle, supports more effective separation of blood components and better isolation of platelets and the signalling molecules they contain.

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Administration of Liquid PRF

The prepared liquid PRF is injected into the areas of the scalp showing thinning or hair loss. The procedure is minimally invasive, generally well tolerated, and doesn’t require downtime, so most people return to their normal activities straight after.

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Low-level Laser Light

Many PRF sessions conclude with low-level laser light therapy, which supports local blood flow and cellular activity at the treatment site. This non-invasive step is typically painless and is used alongside PRF to support the scalp’s healing response.

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Is PRF Right for You? What a Consultation Covers

PRF isn’t suitable for everyone, and suitability is only confirmed through a proper medical assessment. A consultation with our practitioner will cover your hair and scalp history, general health, and any of the following factors that may affect candidacy:

  • Pregnancy or breastfeeding
  • History of cancer or autoimmune disease
  • History of severe allergic reactions
  • Active infection or inflammation
  • Bleeding disorders or anticoagulant therapy
  • Immunosuppressive therapy

Your practitioner will also discuss how PRF may fit alongside other elements of a broader hair and scalp plan, such as scalp hydration, gentle conditioning products, nutritional factors, and low-level laser therapy. Any prescription-only options are only considered following individual consultation with a registered health practitioner.

If you’re still assessing your hair loss pattern before booking a consultation, our articles on early signs of hair loss in men and women and decoding the hair loss treatment process may help you understand what to look for.

What to Expect During and After Treatment

PRF injections may cause mild discomfort or a brief stinging sensation, and are usually well tolerated without topical or local anaesthetic. Your practitioner will explain possible temporary effects such as redness, tenderness, swelling or bruising at injection sites, so you can plan around work, exercise, or your hair care routine in the days following.

There’s no required downtime, though your practitioner may suggest simple aftercare steps to support your scalp’s recovery.

Results

Some people notice gradual changes over several months as part of ongoing care; others may take longer or need plan adjustments. Individual results vary.

Patient images shown below are from the video ‘ENGLISH – PRF in Aesthetics, Plastic Surgery & Dermatology’ by Process for PRF, available at here. Accessed on [20th August 2024]. Images are illustrative; lighting/angles/timeframes vary and they are not intended to predict individual outcomes.

FAQs

Platelet-rich fibrin is a concentrate prepared from your own blood, containing platelets, growth factors and cytokines held within a natural fibrin matrix. It’s used in regenerative and tissue-repair protocols, including as a PRF hair treatment for scalp and follicle support.

The main differences are in preparation and release. PRF retains the natural clotting process and forms a fibrin scaffold that releases growth factors gradually, while PRP uses anticoagulants to prevent clotting and is generally dispersed more quickly. PRF’s centrifugation protocol also differs, using slower speeds over a shorter period.

We usually recommend a PRF session once a month for the first three months, where appropriate for the individual. Some people and their practitioner may then consider ongoing sessions every three to four months for maintenance. Your practitioner will confirm a schedule based on your scalp assessment, diagnosis and goals, and this may be adjusted over time.

Recovery from PRF is generally straightforward. Mild redness, tenderness or minor swelling at the injection sites is possible in the short term, and most people resume normal activities immediately. Your practitioner will run through specific aftercare guidance relevant to your treatment.

  • 1 session: $400
  • 2 session pack: $700 ($350 per session)

Pricing is a guide only and may change over time. Any additional supportive treatments, such as topical serum, supplements or in-clinic therapies, will be discussed with you before proceeding.

Combination approaches are common in hair and scalp care, though your practitioner will need to assess your hair, scalp and medical history before recommending a plan. This might include gentle scalp products, nutritional considerations, low-level laser therapy, or other clinically supported options where appropriate.

Some people notice mild discomfort or a brief stinging sensation during injections, but the procedure is generally well tolerated without anaesthetic. Your practitioner will talk you through what to expect and any temporary side effects beforehand.

Yes. PRF may not be suitable for people who are pregnant or breastfeeding, have a history of cancer or autoimmune disease, severe allergic reactions, active infection or inflammation, bleeding disorders, or who are on anticoagulant or immunosuppressive therapy. A full medical evaluation with a qualified practitioner is required before proceeding.

Book a PRF Consultation

PRF treatment for hair loss starts with a proper consultation, not a booking. Our practitioners will assess your scalp and hair condition, talk through whether PRF is appropriate for you, and outline what a realistic treatment plan could involve.

This page is only intended to provide factual information to educate individuals who are interested in learning more about the treatment. Our clinic offers a health-practitioner-led consultation. Depending on the outcome of the consultation, this may or may not lead to the provision of a prescription.